Michael also starred in the long-running TV sitcom Spin City, which aired some five years after he was diagnosed with Parkinson’s. At the height of his career, and at only 29 years old, Fox found himself suffering from the disease, and he kept it a close secret until he finally disclosed it to the public in 1998.

In the year 2000, he briefly stopped acting in order to tend to his illness, but throughout the years he has still maintained an impressive body of work in film, TV, and voiceover.

He founded the Michael J. Fox Foundation, which is dedicated to Parkinson’s research, and the work he’s done has advanced studies in the disease and brought a huge amount of attention and awareness to it. In an episode of Curb Your Enthusiasm, Michael famously plays himself and displays a hilarious sense of humor about his condition. It’s a fan-favorite episode of the series.

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